Ischemic injury refers to damage caused by a lack of blood flow and oxygen to a specific area of the body, typically due to a blood clot or blockage in an artery. This can lead to cell death and tissue damage, particularly in organs such as the heart, brain, or limbs. Ischemic injury can have serious consequences, such as stroke, heart attack, or tissue necrosis. Research in this area focuses on understanding the mechanisms of ischemic injury, identifying potential treatments or interventions to minimize damage, and improving outcomes for individuals who experience ischemic events.